GLOSSARY

Listed below are many of the words you may come across concerning your disease.

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Abscess

A localised collection of pus in a cavity formed by the decay of diseased tissues.

Acute

Sudden onset of symptoms (as in relapse).

Aetiology

Cause.

Anaemia

A reduction in the number of red cells, haemoglobin (iron) or volume of packed red cells in the body.

Anastomosis

The joining together of two ends of a healthy bowel after a diseased bowel has been cut out (resected) by the surgeon.

Ankylosing Spondylitis

Chronic inflammatory disease of the spine and nearby joints, which can cause pain and stiffness in the spine, neck, hips, jaw and rib cage.

Anus

The opening to the back passage.

Arthralgia

Pains in the joints.

Arthritis

Inflammation of a joint(s) with pain, swelling and stiffness.

Ascending Colon

The portion of bowel extending from the caecum to the hepatic flexure.


Biopsy

Removal of small pieces of tissue from parts of the body (e.g. colon - colonic biopsy) for examination under the microscope for diagnosis.

Caecum

The first part of the large intestine forming a dilated pouch into which opens the ileum, the colon and the appendix.

Chronic

Symptoms occurring over a long period of time.

Cobblestoning

Characteristic appearance of the bowel mucosa (lining) seen in Crohn's disease (like 'cobblestones') formed from deep ulceration and swelling of the surrounding tissue.

Colitis

Inflammation of the colon

Colon

The large intestine extending from the caecum to rectum. It has an ascending, transverse and descending portion.

Colonoscopy

Inspection of the colon by an illuminated telescope called a colonoscope.

Colostomy

Surgical creation of an opening between the colon and the surface of the body. Part of the colon is brought out onto the abdomen creating a stoma. A bag is placed over this to collect waste material.

Constipation

Infrequent or difficulty in the passage of bowel motions.

Crohn's Activity Index

Measurement of the severity of active disease using symptom scores which are monitored over one week.

Defaecation

The act of passing faeces.

Descending Colon

The portion of bowel between the splenic flexure and the sigmoid colon.

Diarrhoea

An increase in frequency, liquidity and weight of bowel motions (normal production * 200g in 24 hours)

Distal

Further down the bowel towards the anus.

Diverticulum (plural diverticula)

Small pouch-like projections through the muscular wall of the intestine which may become infected, causing diverticulitis.

Dysplasia

Alteration in size, shape and organisation of mature cells that indicate the possible development of cancer.

Electrolytes

Salts in the blood, e.g. sodium, potassium, calcium.

Enema

A liquid, (e.g. Barium or steroid) introduced into the rectum for treatment or diagnostic purposes to stimulate the production of a bowel motion.

Endoscopy

A collective name for all visual inspections of body cavities with an illuminated telescope. Examples are:

- Gastroscopy
- Colonoscopy
- Sigmoidoscopy

Erythema Nodosum

Red, tender swellings occasionally seen on the shins and lower legs during a flare-up of inflammatory bowel disease. They usually subside when the disease is in remission.

Erythrocytes

Red cells in the blood which carry oxygen in haemoglobin.

Exacerbation

An aggravation of symptoms.

Faeces

The waste matter eliminated from the anus (other names - stools, motions).

Fibre Optic

Flexible fibres which carry light, e.g. in a colonoscope

Fissure

A cleft or groove (crack) in the skin surface, (e.g. in the anus - anal fissure).

Fistula

An abnormal connection, usually between two organs, or leading from an internal organ to the body surface, (e.g. between the anus and skin surface - anal fistula).

Flatus

Gas from the rectum.

Fulminant Colitis

Colitis occurring suddenly with great intensity and severity.

Granulomas

Nodules of cells, surrounded by lymphocytes which can be found in all layers of the bowel. If present, they strongly suggest Crohn's disease.

Haemorrhoids

Swollen veins in the area of the anus which bleed easily and are often painful. (Similar to varicose veins in the legs).

Haematochezia

The passage of bloody stools.

Harvey and Bradshaw Index

Modified simple measurement of disease activity in Crohn's disease measured over a 24 hour period.

Hepatic Flexure

The portion of the colon at which the ascending and the transverse colon meet, below the liver.

Heredity

The transmission of characteristics from parent to child.

Histology

The examination of tissues under the microscope to assist diagnosis.

Hypoalbuminaemia

Decreased albumin (protein) in the blood.

Hypokalaemia

Decreased potassium in the blood.

Ileo-Anal Anastomosis

The formation of a pouch following colectomy by re-fashioning loops of ileum into a reservoir making an artificial rectum and joining it to the anus. (Park's Pouch).

Ileostomy

This is when the open end of the healthy ileum is diverted to the surface of the abdomen and secured there to form a new exit for waste matter.

Inflammation

A natural defence mechanism of the body in which blood rushes to any site of damage or infection leading to reddening, swelling and pain. The area is usually hot to touch.

Iritis

Painful inflammation of the eyes.

Laxative

An agent that acts to cause emptying of the bowel. This may be by purging (irritating the lining) or increasing the volume of stool (bulking).

Lesion

A term used to describe any structural abnormality in the body.

Leucocytes

White cells in the blood which help fight infection.

Leucocytosis

An increase in the number of circulating white cells in the blood.

Leucopenia

A decrease in the amount of circulating white cells in the blood.

Mucus

A white, slimy lubricant produced by the intestines. It is found in excess in the stools of patients with colitis.

Oedema

Accumulation (build up) of excessive amounts of fluid in the tissues resulting in swelling.

Osteoporosis

Thinning of the bones due to calcium loss. May be caused by long-term use of steroids or low levels of oestrogen.

Pathogen

Harmful organism causing disease.

Pathology

The study of the cause of disease.

Perforation

An abnormal opening (hole) in the bowel wall which causes the contents of the bowel to spill into the normally sterile abdominal cavity.

Peritoneum

The membrane lining the abdominal cavity.

Peritonitis

Inflammation of the peritoneum, often due to a perforation.

Pouchitis

Inflammation of an ileo-anal pouch.

Polyp

A protruding growth from mucous membrane, (e.g. colonic polyp - in the colon).

Prophylaxis

Treatment to prevent a disease occurring before it has started.

Proximal

Further up the bowel towards the mouth.

Pyoderma Gangrenosum

A type of chronic skin ulceration which sometimes occurs on the limbs of people with inflammatory bowel disease.

Radiologist

The doctor who interprets X-Ray pictures to make a diagnosis.

Rectum

The lower 20cm of the large intestine, above the anus.

Relapse

Return of disease activity.

Remission

A lessening of symptoms of the disease and return to good health.

Sigmoid

The portion of the colon shaped like a letter 'S' or 'C' extending from the descending colon to the rectum.

Sigmoidoscopy

Inspection of the sigmoid colon with an illuminated telescope called a sigmoidoscope.
Skip Lesions

Areas of normal bowel mucosa between areas of inflamed bowel mucosa (seen in Crohn's disease).

Splenic Flexure

The portion of the colon at which the transverse and the descending colon meet, below the spleen.

Steatorrhoea

Presence of excess fat in the stools.

Stricture

The narrowing of a portion of the bowel.

Suppository

A bullet-shaped solid medication put into the rectum.

Tenesmus

Persistent urge to empty the bowel caused by an inflamed rectum.

Terminal Ileum

The last part of the ileum joining the caecum via the ileo-caecal valve.

Toxic Megacolon

A dilatation (swelling) of the colon which may led to perforation, usually in a very severe attack of ulcerative colitis or Crohn's disease. Urgent surgery is almost always performed.

Transverse Colon

The portion of bowel between the hepatic and the splenic flexures.

Tumour

An abnormal growth which may be benign (non-cancerous) or malignant (cancer).

Ultrasound

Use of high-pitched sound waves to produce pictures of organs on a screen for diagnostic purposes, by passing a transducer with conducting jelly over a specified body cavity, (e.g. the abdomen - abdominal ultrasound).