PYODERMA
GANGRENOSUM |
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What is it? Pyoderma gangrenosum is a chronic skin ulceration occurring usually on the legs but can appear anywhere on the body. Pain may be apparent before the ulcers appear. They may also drain pus-like fluid but are not usually infected. What is the cause? The condition is usually associated with inflammatory bowel disease and is more common in ulcerative colitis (1-5%) than Crohn's disease (1-2%). It is also often related to an injury, or following an injection in the affected area. It can occur independently of active disease although pancolitis is found in 85% of patients with the condition. What is the treatment? Treatment of the underlying inflammatory bowel disease is often successful in resolving the skin lesions. Medical treatments may be tried, such as: • topical
antibiotics However,
the lesions may return. Colectomy provides a cure in most cases of
persistent, troublesome lesions. | ||